The present invention provides a kind of Tripterygium extract and active ingredients for drug preparation activity and function regulation of retinoid X receptor, retinoid X receptor for the screening of Tripterygium extract and active ingredients contained, as well as the retinoid X receptor used for structural modification of active ingredients contained in the guidance of Tripterygium wilfordii. At the same time, the invention discloses Tripterygium active ingredient is through interaction induced by heat shock protein HSP70 and nuclear receptor RXR alpha RXR alpha, thereby regulating the transcriptional activity of HSP70 dependent, which provides a new pathway for screening alpha activity screening of RXR related drugs.
【技术实现步骤摘要】
【技术保护点】
一种雷公藤提取物的应用，其特征在于，所述雷公藤提取物用于制备调控视黄醇Ｘ受体的活性与功能的药物。
【技术特征摘要】
【专利技术属性】
技术研发人员：陆炯明，陈洁，曾锦章，张晓坤，
申请(专利权)人：中国科学院上海生命科学研究院，上海生茂投资有限公司，
类型：发明
国别省市：31[中国|上海]
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